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September 2022 -
Volume 20, Issue 9


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From the Editor

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Prevalence of depressive symptoms in hypertensive patients in Taif city
[Abstract]
[pdf]

Ayman A. Atalla, Rana S. AlQarni, Reema S. Althubaiti, Kholoud A. Alhasani, Bushra S. Alghamdi, Hadeel S. Alghamdi
DOI: 10.5742/MEWFM.2022.9525131

Patient Awareness about the indications for and complications of sleeve gastrectomy in the western region of Saudi Arabia
[Abstract]
[pdf]

Khalid M. Alzahrani, Jamal Amin Faydh, Saad Eidhah Althuwaybi, Saud Saeed Alzahrani, Fayez Dakhil Allah Althobaiti, Bader Abed Althagafi
DOI: 10.5742/MEWFM.2022.9525132

Prevalence of Obstructive Sleep Apnea among Patients with Cardiovascular Diseases
[Abstract]
[pdf]

Reda Abdelmoaty Goweda, Mahmoud Elshahat Elsayed, Asmhan Saadeldin Rady, Faisal Saleh Alnahdi, Anas Mohammad Alqurashi,
Turki Talal Alessa, Bassam Musleh Bin Laswad, Azzam Musleh Bin Laswad, Omar Abdulaziz Althobity, Ammar Safran Alhothali, Abdullah Khafagy,
Ahmed Metwally, Wael Zeid
DOI: 10.5742/MEWFM.2022.9525133

Efficacy of oral isotretinoin in the treatment of acne vulgaris
[Abstract]
[pdf]

Amer Bin Al-Zou, Asia Hassan Abdulla Saleh, Mohamed Saeed Bafadhl, Fathi Elkasah
DOI: 10.5742/MEWFM.2022.9525134

Leakage Management after Laparoscopic Sleeve Gastrectomy: A Tertiary Center Experience in Saudi Arabia
[Abstract]
[pdf]

Khalid M. Alzahrani, Tamer M. Abdelrahman, (Sumayyah A. Jafri, Mohammed Abdo, Khalid A. Alsharif
DOI: 10.5742/MEWFM.2022.9525135

Population and Community Studies

The monitoring of DOACs in primary care, a quality improvement project
[Abstract]
[pdf]
Abdul Muhid, Javed Khan
DOI: 10.5742/MEWFM.2022.9525136

The level of knowledge and awareness about diabetes and diabetic foot among the Taif general population
[Abstract]
[pdf]

Haifa Alotaibi, Areej M. Abdullah, Rawan I. Alqurashi, Kholood S. Althobaiti, Sarah A. Khan, Shumukh G. Althobaiti
DOI: 10.5742/MEWFM.2022.9525137

Hypertensive and Diabetic Patients' Knowledge of Myocardial Ischemia and Stroke Symptoms in Al-Ahsa, Saudi Arabia
[Abstract]
[pdf]
Abdullah AI Ali, Fatimah Aledili, Fatimah Albahrani, Heba Albisher, Fatimah Bomouzah, Fatimah Aleliwi, Ghadeer Alghasham, Laila Alalawi
DOI: 10.5742/MEWFM.2022.9525138

Health-related behaviors of undergraduate medical students of public sector university, Karachi 2022
[Abstract]
[pdf]

Sahar Aijaz, ,Ali Jawwad Karim, ,Fatima Abid, ,Aarfa Azhar, Maha Noor,
Summaiya Ali Muhammad
DOI: 10.5742/MEWFM.2022.9525139

Awareness of benign paroxysmal positional vertigo among the population of Taif city
[Abstract]
[pdf]

Mohammed A. Basurrah, Yahya A.Fageeh, Sultan H. Alziyadi, Abdulsalam M. Alshehri, Waleed Khalid Alrabie, Meshari M. Alruways, Ahmad S. Alosaimi, Faisal M. Alfadli
DOI: 10.5742/MEWFM.2022.9525140

Knowledge, Attitude, and Practice of Pregnant Women Regarding the Possible Effects of Obesity on Maternal and Fetal Health
[Abstract]
[pdf]

Sahar Ali Sari, Yahia Mater Al-Khaldi, Amal Mohammed Surrati, Ajaeb Meshal Alharbi
DOI: 10.5742/MEWFM.2022.9525144

Assessment of satisfaction level among patients toward services provided by dental clinics: A cross-sectional study
[Abstract]
[pdf]

Nada Fahad Saleh Al Ateeq, Budur Abdullah Mohammad Aljalban, Nawal Fahad Saleh Alazmi, Ashwaq Abdullah Mohammad Aljalban, Talal Awad A Alharbi, Mona Rubayyi R Alanazi
DOI: 10.5742/MEWFM.2022.9525156

Regional Covid

Concomitant COVID 19 Infection And NTDS: 68 Patient Case Series
[Abstract]
[pdf]

Sarab K. Abedalrahman, Fatima K. Khalid, Mahabad. S. Ali, Sheelan MS. Hasan
DOI: 10.5742/MEWFM.2022.9525142

Psychoneurotic symptoms among COVID infected patients; case series study
[Abstract]
[pdf]

Mohammed Khalil Ibraheem, Sarab K. Abedalrahman, Ashoor R Sarhat
DOI: 10.5742/MEWFM.2022.9525143

Review

Clinical Aspects of Breast Cancer
[Abstract]
[pdf]

Hani Raka Karrar, Mahmoud Ismail Nouh, Badriah Mohammed Alanazi,
Amro Othman Ahmed Hakami, Wejdan Jamaan S Alzahrani,
Waleed Khalid Aldoweirah, Waleed Salman Alanazi, Nasser Emad Alshammari, Bassam Mohammed Alanazi, Rahaf abed Alharbi, Njood Hamad Alshammari, Hadeel Saleh Alzahrani, Abdullah Salem A Alghamdi, Fahad Wadi Alanazi
DOI: 10.5742/MEWFM.2022.9525148

Over time prevalence of illicit substance use in Saudi Arabia
[Abstract]
[pdf]

Abdulrahman Alfaifi, Maged El-Setouhy
DOI: 10.5742/MEWFM.2022.9525150

Case Report

Osteoid osteoma of the proximal femur: A case report
[Abstract]
[pdf]

Ameena Khalid Bughamar, Noora Hamad Alaazmi, Fahad Alkhalifa
DOI: 10.5742/MEWFM.2022.9525152

HEADACHE - Common symptom with Rare Diagnosis in UK Primary Care - A Case report
[Abstract]
[pdf]

Syed Mohsin Raza, Syed Shahinul Haque
DOI: 10.5742/MEWFM.2022.9525153

Original Clinical Research

Necrotizing Fasciitis of Spine: The knowledge of physicians in Saudi Arabia toward this rare condition
[Abstract]
[pdf]

Alshehri A. Mohammed
DOI: 10.5742/MEWFM.2022.9525156

Middle East Quality Improvement Program
(MEQUIP QI&CPD)


Chief Editor -
Abdulrazak Abyad MD, MPH, MBA, AGSF, AFCHSE

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Publisher -
Lesley Pocock
medi+WORLD International
AUSTRALIA
Email
: lesleypocock@mediworld.com.au
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September 2022 - Volume 20, Issue 9

Efficacy of oral isotretinoin in the treatment of acne vulgaris

(1) Associate Professor of Dermatology, Faculty of Medicine, University of Aden, Yemen
(2) Associate Professor, Department of Dermatology, College of Medicine, Hadhramout University, Yemen
(3) Associate Professor, Department of Dermatology, Faculty of Medicine, Sirte University, Libya

Corresponding author:
Dr. Amer Bin Al-Zou
Associate Professor of Dermatology; Faculty of Medicine, University of Aden, Yemen
Email: amer_zou2009@yahoo.com

Received: July 2022 Accepted: August 2022; Published: September 1, 2022. Citation: Amer Bin Al-Zou et al. Efficacy of oral isotretinoin in the treatment of acne vulgaris. World Family Medicine. 2022; 20(9): 41-50. DOI: 10.5742/MEWFM.2022.9525134

Abstract


Background:
Acne vulgaris is a chronic inflammatory disease of pilosebaceous
units.

Objective: To assess the presentation of acne vulgaris and to evaluate the efficacy of oral isotretinoin therapy,

Materials and method: This was a retrospective chart review of patients presenting to the dermatology private clinic in Almansoora, Aden, over a 2-year period, who complained of acne vulgaris and were treated with oral isotretinoin.

The collected data were analyzed by SPSS version 17. P-value < 0.05 was considered as statistically significant.

Results: The total study patients were 86 (68.6% females and 31.4% males).

The mean age of patients was 25.6 ± 7.9 years. The difference between means related to sex shows statistically significant (p = 0.006).

The patients of the age group 20 years were predominant with (70.9%).

The most common side effects were cheilitis (54.7%) followed by dry-skin (12.8%), acne flaring (9.3%), hair loss (7.0%) and the lowest side effect was increased liver enzyme in (1.2%) patients. Papulonodular of acne vulgaris is the most common severity type (36.1%) followed by comedones, papules, pustules (32.5%).

Comedones, papules, pustules are more common in the age group < 20 years of age (24.4%) while papulonodular are more common in the age group 20 years with (33.7%). The difference between values of severity types of acne vulgaris related to age groups is statistically highly significant (p = 0.000).

Complete clearance occurred in (80.2%) patients followed by partial clearance. Partial clearance was found in (16.3%) patients, most of them treated within 16 weeks (12.8%). The difference between values of therapy response of patients in relation to therapy duration is statistically highly significant (p = 0.000).

Conclusion: The results of our study show that isotretinoin is a safe and effective therapy for acne vulgaris with few side effects.

Key words: Efficacy, isotretinoin, treatment, acne vulgaris, Aden







 


 

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