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Abstract
Background: We
tried to understand the safest value of
triglycerides in the plasma.
Methods: Patients
with plasma triglycerides values lower
than 60 mg/dL were collected into the
first, lower than 100 mg/dL into the second,
lower than 150 mg/dL into the third, lower
than 200 mg/dL into the fourth, and 200
mg/dL and greater into the fifth groups.
Results: The
study included 669 cases (393 females),
totally. Mean age increased up to triglycerides
value of 200 mg/dL, and there was an increase
of triglycerides about 8.1 mg/dL for each
year of aging. Male ratio increased parallel
to increased triglycerides, gradually
(32.3% versus 50.0%, p<0.001). Mean
body mass indexes were 24.4, 27.0, 29.3,
29.9, and 30.1 kg/m2 in the five groups,
respectively, and it was normal only in
cases with the plasma triglycerides values
of lower than 60 mg/dL. Fasting plasma
glucose, hypertension, diabetes mellitus,
smoking, and chronic obstructive pulmonary
disease increased parallel to increased
triglycerides, gradually, whereas low
density lipoproteins and white coat hypertension
increased just up to triglycerides value
of 200 mg/dL. The greatest number of deteriorations
(seven components, significantly) was
observed just during passage from the
first into the second groups.
Conclusions:
Plasma triglycerides may actually be some
acute phase reactants indicating disseminated
endothelial damage, inflammation, fibrosis,
and eventual atherosclerosis all over
the body. There may be some significant
relationships between plasma triglycerides
and aging, excess weight, and smoking.
The greatest number of deteriorations
of components of metabolic syndrome were
observed just above triglycerides value
of 60 mg/dL.
Key words:
Triglycerides, acute phase reactants,
smoking, excess weight, aging, chronic
endothelial damage, accelerated atherosclerosis
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