JOURNAL
Current Issue
Journal Archive
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October 2021 -
Volume 19, Issue 10


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From the Editor

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Attitude and practice of pregnant women living in Saudi Arabia, about COVID-19 in relation to pregnancy outcome
[Abstract]
[pdf]
Rehab Alsaleh, Fatima Mohammed Faraj, Ahlam Ahmed Aldcgha, Bashair Mohammed Omar, Elaf Hussein bin Mahfouz, Amjad Zaki
DOI: 10.5742/MEWFM.2021.94132

Quarantine COVID-19 compliance in families with an allergic and immunological diseased child and its psychological impact in KSA
[Abstract]
[pdf]
Ghaida T Alrabaiai, Abeer H. Alharthi, Jawaher SH. Alotaibi, Nada E. ALgethami, Bushra F. Alshehri, Aymen A. Atalla
DOI: 10.5742/MEWFM.2021.94146

Special editorial

The Scar is your Signature - Announcing details of FREE Skin Surgery Skills ZOOM Webinars for our readers
[Abstract]
[pdf]
Lesley Pocock

Original Contribution

Awareness of General Population of Saudi Arabia toward Diabetic Complications
[Abstract]
[pdf]
Mansuor Ahmed Alanazi, Abdullah Ibrahim Almutaz, Saleh Essa Aldhwain, Bassam Ali Alasmari, Shoug Mohammad Alfarhan, May Yahya Barakat, Yahya Hassan Almalki, Reem Abdullah ALmousa DOI: 10.5742/MEWFM.2021.94134

Etiologies of Lumbar Puncture Refusal in Pediatric Patients in Children's Hospital, Taif City, Saudi Arabia. A Cross-Sectional Study
[Abstract]
[pdf]
Sara Safar Alrebaiee, Jamal Samear farahat
DOI: 10.5742/MEWFM.2021.94135

Improving patient centered care by documenting their contribution in the plan of care at west bay health center, Qatar
[Abstract]
[pdf]
Wafaa Musallam, Hisham Abdulmoniem, Salma Elnour, Rouba Alkadi, Alawiya Gadallah, Azher Abbas Syed, Wafaa Yousuf
DOI: 10.5742/MEWFM.2021.94136

Pathological factors and associated clinical outcomes of patients with urothelial neoplasms treated at King Adulaziz University Hospital : a single center experience
[Abstract]
[pdf]
Marwan Al-Hajeili, Reem K. Ujaimi, Omar Iskanderani, Mohammad Attar, Ehab Ahmed, Maha A. Safhi, Wejdan T. Almrzouqi, Bashaer A. Alsaati
DOI: 10.5742/MEWFM.2021.94137

Impact of inhalation therapy on occurrence of oral manifestations in patients with bronchial asthma, in Jeddah, Saudi Arabia
[Abstract]
[pdf]
Fathi El-Gamal, Asim Rashid, Heetaf Saeed, Hind Alluheibi, Rotana Qari, Rahaf Baziyad
DOI: 10.5742/MEWFM.2021.94138

Population and Community

Association between obesity and mental disorders among male secondary school students in Abha, Kingdom of Saudi Arabia: A Predictor based Cross-Sectional Study

[Abstract]
[pdf]
Mubarak M.A. Alshahrani, Mohammed Al-Masoudi, Eman M. Alshahrani, Abdulrahman M. Alshahrani, Khalid M. Alshehri, Suliman A. Asiri, Ahmed M. Asiri, Ahmed A. Asiri, Ahmed H. Alabdali
10.5742/MEWFM.2021.94139

Knowledge and practice among primary care physicians in Najran (south west region), Saudi Arabia regarding Maturity Onset Diabetes of the Young (MODY)
[Abstract]
[pdf]
Mohammed Ayed Huneif
DOI: 10.5742/MEWFM.2021.94140

Level of Parental Awareness Regarding Aerodigestive Pediatric Foreign Bodies, Western Region, Saudi Arabia
[Abstract]
[pdf]
Nada E. Algethami, Abeer I.Alsulaimani, Wahaj A. Altalhi, Layla M. Alkhaldi,
Eman S. bayoumy
DOI: 10.5742/MEWFM.2021.94141

Prevalence of dry eye symptoms and risk factors in Saudi Arabia
[Abstract]
[pdf]
Abdulrahman Al-Amri, Sultan Mohammed Abdullah Alkorbi, Abdulrahman Nasser Alqahtani,
Bandar Mohammed Mushabbab Asiri, Abdullah Fahad Alahmari, Turki bjad alotaibi

Prevalence of Generalized Anxiety Disorder among Adults in Primary Health Care in Qatar: A Cross-Sectional Study
[Abstract]
[pdf]
Hani Abdalla, Hassan Tawfik, Ahmed Alnuaimi , Ibtihal Elzaki, Mustafa Mohamed, Tasnim Mobayed, Fatima Alshibani, Safa Zain, Eman Abdelkarim , Nagham Alsmady, Muna Taher
DOI: 10.5742/MEWFM.2021.94148

Education and Training

Epley's Maneuver in Primary Care: A Quality Improvement Project
[Abstract]
[pdf]
Muhammad Hameed, Shabana Shaheen, M Imran Malik, Yousef Essam Hassan Qabeel
DOI: 10.5742/MEWFM.2021.94142

Review

A Review on the Clinical Potential of Lorcaserin in the Treatment of Obesity
[Abstract]
[pdf]
Muhammad Danial bin Daud
DOI: 10.5742/MEWFM.2021.94143

Evaluation and Approach of a Painful Quiet (Non-Red) Eye:
A Comprehensive review for Primary Health Care Physicians

[Abstract]
[pdf]
Shahd A. Al Mahfud, Abdulrahman F. Algwaiz, Lujain S. Alfayez, Ali A. AlSaeed, Turki A. Bin Dakhil
DOI: 10.5742/MEWFM.2021.94149

Knowledge of school teachers regarding Asthma in Aseer region of Saudi Arabia
[Abstract]
[pdf]
Zeinh Hussein Fardan, Abdulbari Ahmed Alzahrani, Sara Abdullah Althumairy, Hana Saeed Al Malih, Shahad Awad AlQahtani, Wijdan Saleh Quraishi, Hasnaa Abdullah Althumairy, Fajr Abdulhadi Alnaami, Wafaa Sulaiman Alhifzi
DOI: 10.5742/MEWFM.2021.94151

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Middle East Quality Improvement Program
(MEQUIP QI&CPD)


Chief Editor -
Abdulrazak Abyad MD, MPH, MBA, AGSF, AFCHSE

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Publisher -
Lesley Pocock
medi+WORLD International
AUSTRALIA
Email
: lesleypocock@mediworld.com.au
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October 2021 - Volume 19, Issue 10

A Review on the Clinical Potential of Lorcaserin in the Treatment of Obesity

Correspondence :
Dr. Muhammad Danial bin Daud
Flat 105 Clifton Court,
Northwick Terrace,
NW8 8JA,
London
Tel: +447809472084
Email: dr.dandaud@gmail.com

Received: September 2021; Accepted: September 2021; Published: October 1, 2021. Citation: Muhammad Danial bin Daud. A Review on the Clinical Potential of Lorcaserin in the Treatment of Obesity. World Family Medicine. 2021; 19(10): 124-128 DOI: 10.5742/MEWFM.2021.94143

Abstract

Obesity is a chronic disease characterized by excessive fat accumulation and associated with impaired metabolism and cardiovascular disease. The high global prevalence of obesity has resulted in the production of anti-obesity drugs over the last couple of decades, normally to be used in combination with lifestyle modifications such as physical activity and diet. One such medication is lorcaserin, a selective serotonin 5-hydroxytryptamine2C (5-HT2C) receptor agonist approved by the FDA in 2012 as a drug therapy for weight management in conjunction with lifestyle modifications. Importantly, the FDA recently issued a request to withdraw lorcaserin from the market as it may promote certain types of cancers, including pancreatic, colorectal, and lung, but further clinical data is being collected and analyzed to assess its carcinogenic risk. This review will address lorcaserin’s therapeutic potential for the treatment of obesity, considering the pre-clinical and clinical trials describing its efficacy in weight loss along with its adverse carcinogenic effects to ultimately determine the likelihood of its reintroduction into the market.

Key words: Lorcaserian, obesity, carcinogenic risk







 


 

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