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March 2022 -
Volume 20, Issue 3


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From the Editor

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Prevalence of depression and anxiety among patients with breast cancer: a cross-sectional study
[Abstract]
[pdf]
Abbas Bukhari, Ali Farsi, Fawaz Albaqami, Abdulaziz Jowharji, Mansoor Radwi, Abdalmohsen Albaqami, Mohammed Fallatah, Abdullah Alammari, Waleed Alghamdi
DOI: 10.5742/MEWFM.2022.952506

Women's Expectations and Satisfaction with the Quality of Antenatal Care at the Primary Health Care Centers in Unaizah City
[Abstract]
[pdf]
Sadeem Alrobiaee, Saulat Jahan
DOI: 10.5742/MEWFM.2022.952507

Pulmonary hypertension and chronic obstructive pulmonary disease in sickle cell diseases
[Abstract]
[pdf]
Mehmet Rami Helvaci, Engin Altintas, Atilla Yalcin, Orhan Ekrem Muftuoglu,
Abdulrazak Abyad, Lesley Pocock
DOI: 10.5742/MEWFM.2022.952508

Positive and negative acute phase reactants in sickle cell diseases
[Abstract]
[pdf]
Mehmet Rami Helvaci, Engin Altintas, Atilla Yalcin, Orhan Ekrem Muftuoglu, Abdulrazak Abyad, Lesley Pocock
DOI: 10.5742/MEWFM.2022.952509

Population and Community Studies

An Overview of Biological Warfare and SARS-CoV-2 as a Potential Biological Agent
[Abstract]
[pdf]
Basem Mohammad Mansour, Deaa Mohammad Alsoleman, Suhail Haydar Alghanem
DOI: 10.5742/MEWFM.2022.9525010

Clinical Audit on Well Baby Services at Primary Health Care Corporation, Qatar
[Abstract]
[pdf]
Noora Alkubaisi, Ansif Pallath Majeed, Hanan Al Mujalli, Abdul Ali Shah,
Sharifullah Khan, Manickavalli M S Anand, Mohammed Asif AbdulGafoor
DOI: 10.5742/MEWFM.2022.9525012

Letter to the Editor

MENA Stem Cells Forum

News Alert

Fake Covid vaccine found in Iran - and beyond?
[Abstract]
[pdf]
Lesley Pocock
DOI: 10.5742/MEWFM.2022.9525016

Review


Cystic Fibrosis: A Review Article
[Abstract]
[pdf]
Hani Raka Karrar, Mahmoud Ismail Nouh, Abdulmohsen Aqeel G. Alanazi,
Sultan Essa Alharbi, Fahad Nuwayfi Almutairi, Hussain Ali Abdullah Alhammad,
Abdullah Ali Hassan Sadeeg, Mohammed Aljunaid Alamin Alsheikh,
Wafa mohammed alshaikh, Mohammed yousef Alyahya, Wejdan Ali Sulieman makki, Hashima Mohammed Alhazmi,
Amal saleem Almutairi, Rehab Salah Aldin Alhendi
DOI: 10.5742/MEWFM.2022.9525014

Case Report

Early-onset CTCL, localized and unilateral - case review

[Abstract]
[pdf]
Ebtisam Elghblawi
DOI: 10.5742/MEWFM.2022.9525015

Original Clinical Research

Study the clinical futures of vitiligo among Yemeni patients in Aden
[Abstract]
[pdf]
Asia Hassan Abdulla Saleh, Amer Bin Al-Zou
DOI: 10.5742/MEWFM.2022.9525017

Surgical treatment and Survival of Gallbladder Cancer Patients: A Systematic Review
[Abstract]
[pdf]
Ali Ibrahim A. Alshehri
DOI: 10.5742/MEWFM.2022.9525019

Shared Decision-Making and its Impact on Medication Adherence among Hypertensive Patients in Northern Saudi Arabia
[Abstract]
[pdf]
Mutasim Almuayqil, Abdusalam Alghamdi, Fahad Alruwaili, Nashmi Al-Etesh
DOI: 10.5742/MEWFM.2022.9525020

Middle East Quality Improvement Program
(MEQUIP QI&CPD)


Chief Editor -
Abdulrazak Abyad MD, MPH, MBA, AGSF, AFCHSE

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Publisher -
Lesley Pocock
medi+WORLD International
AUSTRALIA
Email
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March 2022 - Volume 20, Issue 3

Early-onset CTCL, localized and unilateral – case review


Corresponding author:

Dr Ebtisam Elghblawi
Specialist dermatologist
Email: ebtisamya@yahoo.com

Received: January 2022; Accepted: February 2022; Published: March 1, 2022. Citation: Ebtisam Elghblawi. Early-onset CTCL, localized and unilateral – case review. World Family Medicine. 2022; 20(3): 64-65. DOI: 10.5742/MEWFM.2022.9525015

Abstract

A 39-year-old man attended with an itchy single rounded red non-scaly skin lesion, with slightly raised edge, on his left leg that was unresponsive to topical steroids for the past two-weeks (figure-1). Apart from that, he had no other complaint. He was fit and well. Examination showed a unilateral localised red slightly-scaly, non-blanchable skin plaque on his lower left leg. Other skin parts were not affected. Physical examination was otherwise unremarkable without any detectable lymhadenopathies.

Based on the clinical examination I could not align this skin lesion to any other dermatological disease. However; I agreed with the patient to take a punch biopsy from the skin lesion that he had presented with, in order to find out the actual pathology.

The histology reading showed perivascular and periadnexal lymphocytic infiltration in the dermis. Some lymphoid cells were larger and neomorphic. There was no exocytosis.

Histopathlogy with immune histochemical profile showed CD-3 positive and CD-20 negative. The report concluded by the histopatholgist that the immunohistochemical profile is consistent with T-cell proliferation and the picture suggests cutaneous T-cell lymphoma. This diagnosis should not be missed. When the condition at its earlier stage, usually it shows erythematous patches with fine scales, however, when it starts to infiltrate, it can involve blood, lymph nodes and many viscera ultimately. It is abnormal lymphocytes proliferation and mostly males predominan with an incidence of 1 per 100,000 per year.







 


 

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