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June 2021 -
Volume 19, Issue 6


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From the Editor

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The prevalence of depression among female medical students in Al-Maarefa Colleges in Riyadh, Saudi Arabia
[pdf]
[Abstract]
Amani Abdullah Alharbi
DOI: 10.5742/MEWFM.2021.94061

Knowledge, Attitude and Practices of Primary Care Physicians in Aseer Region, Saudi Arabia, Regarding Geriatric Depression
[pdf]
[Abstract]
Hassan MH Alqarni, Ayedh AA Alahmari, Hassan MH Alshehri, Hassan AH Asiri,
Ossama A. Mostafa
DOI: 10.5742/MEWFM.2021.94062

The dietary habits and physical activities of undergraduate medical students in Karachi
[pdf]
[Abstract]
Savaira Rehman, Nadira Hyder Zaidi, Tafazzul Hyder Zaidi, Sarah Feroz, Maria Azad, Farah Yasmeen, Sahar Aijaz
DOI: 10.5742/MEWFM.2021.94063

The Effect of caffeine on sleep among medical students at King Faisal University Saudi Arabia
[pdf]
[Abstract]
Ayub Ali, Abdulaziz Albahrani, Ahmed Alnasser, Ali Alsalman, Mohammed Alaithan, Mohammad Alswaidan, Abdulla Alkhalifa
DOI: 10.5742/MEWFM.2021.94065

Population and Community Studies

Psychological impact of Corona Virus Disease on general population in Karachi
[pdf]
[Abstract]
Suman Lohana, Nadira Hyder Zaidi, Tafazzul Hyder Zaidi, Kartaar Saahil, Komal Novlani
DOI: 10.5742/MEWFM.2021.94067

Review

Literature Review: Newborn Hearing Screening May Predict Autism Spectrum Disorder
[pdf]
[Abstract]
Akeil Al-Faraj
DOI: 10.5742/MEWFM.2021.94068

An update on Pathophysiology, Epidemiology, Diagnosis and Management Part 6: Medical Treatment of Early and Advanced Parkinson's Disease: Use of Levodopa
[pdf]
[Abstract]
Abdulrazak Abyad, Ahmed sami Hammami
DOI: 10.5742/MEWFM.2021.94069

Case Report

Multiple Myeloma in Young pregnant patient
[pdf]
[Abstract]
Hanadi Marouf, Nourhan Metwally, Anwar Joudeh, Mansoura Ismail
DOI: 10.5742/MEWFM.2021.94070

Middle East Quality Improvement Program
(MEQUIP QI&CPD)


Chief Editor -
Abdulrazak Abyad MD, MPH, MBA, AGSF, AFCHSE

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Lesley Pocock
medi+WORLD International
AUSTRALIA
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June 2021 - Volume 19, Issue 6

Multiple Myeloma in Young pregnant patient

Corresponding author:
Professor Mansoura Ismail
Family Medicine Department, Faculty of Medicine,
Suez Canal University, Ismailia,
Egypt
Email: Mansoura70@hotmail.com

Received: April 2021; Accepted: May 2021; Published: June 1, 2021. Citation: Hanadi Marouf, Nourhan Metwally, Anwar Joudeh, Mansoura Ismail. Multiple Myeloma in Young pregnant Patient. World Family Medicine. 2021; 19(6): 82-88 DOI: 10.5742/MEWFM.2021.94070

Abstract

Background:
Multiple Myeloma (MM) is a relatively uncommon cancer that accounts for approximately 10 percent of all hematologic malignancies. It is an incurable disease and is behind about 20 percent of mortality from hematologic malignancy and 2 percent of mortality from all cancers. MM is usually characterized by the neoplastic proliferation of plasma cells producing a monoclonal immunoglobulin. The plasma cells proliferate in the bone marrow and can result in extensive skeletal destruction with osteolytic lesions, osteopenia, and /or pathologic fractures. MM is rarely seen in those younger than 35 years old. Despite those in the younger age group having been shown to have a more aggressive course, reportedly they have had similar responses to treatment compared to older patients.

Case: This case is about a young pregnant female who presented to the hospital with body ache and diplopia in her 30th week of pregnancy. Multiple Myeloma type IgA lambda was diagnosed. The baby was delivered prematurely but healthy. The patient was treated initially with bortezomib, cyclophosphamide, and dexamethasone (VCD) regimen along with radiation therapy and chemotherapy. The patient responded well to the treatment.

Conclusion: This case of Multiple Myeloma in a young pregnant female presented with unexplained symptoms and was diagnosed after presentation with neurological symptoms. Treatment with VCD regimen along with radiation therapy and chemotherapy showed excellent response. It highlights that multiple myeloma may present atypically in young patients and early diagnosis is important. The Case report is needed.to determine optimal treatment regimens for this subset of young patients.

Key words: Multiple Myeloma, young, pregnant, diplopia.







 


 

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