Genital
warts in women: Knowledge, Attitude and Behaviour
(KAB)
Literature review and recommendations
Ebtisam
Elghblawi
Correspondence:
Dr Ebtisam Elghblawi MBBCh, MScRes, ADD,
DRH
Email: ebtisamya@yahoo.com
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Abstract
Background: Genital warts is a
common global public problem with considerable
morbidity. GWs are one of the commonest
sexually transmitted diseases (STDs) that
entail considerable morbidity in terms
of social, psychological and economic
consequences.
Objective: to examine the literature
relating to the knowledge and attitudes
of patients and others, and the behaviours
(KAB) connected with GWs.
The search strategy
was conducted through the search key word
"genital wart", "condyloma
acuminate", and "venereal warts",
then combing knowledge and GWs, attitudes
and GWs, behaviours and GWs, in developing
and developed countries, through the e-books,
and
e-journals including EBSCO, Scopus, Cochrane,
life science database, journals, and peer
review, and the English-language literature,
which were applied.
Conclusion: This review demonstrates
a gap in knowledge among many women worldwide
about genital HPV. This varies according
to ethnicity and socio-economic characteristics,
even if women seemed to be educated.
Also it is uncertain if any educational
intervention can change sexual behaviour
relating to HPV acquisition, but at least
awareness is key to preventing infection
and education may urge people to use protective
measures like condoms more consistently.
In terms
of other possible interventions, male
circumcision proved scientifically to
be protective for women against genital
HPV infection.
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Genital human warts (condyloma acuminata) are
caused by human papillomavirus (HPV), which is
primarily sexually transmitted. There are more
than 120 HPV sub-types which have been identified
(Castellsagué, 2008), with 40 which can
infect the genital area. HPV 6 and 11 are the
commonest strains causing GWs. There are 15 oncogenic
types which can infect the cervix, vaginal mucosa
and vulval and anal skin and the two main culprits
are HPV16 and 18 which are associated with more
than 70% of all cervical cancer globally. According
to Anorlu, 2008, and Doerfler et al, 2009, cervical
cancer contains HPV DNA in 100% of cases.
Many studies state that about 15-35% of sexually
active women have subclinical infections with
HPV virus (asymptomatic carriers), and most
of those women usually become negative within
2 years; however those who do not are at greater
risk of develop cervical cancer (Doerfler et
al, 2009).
The incidence of this infection has been on
the rise recently (Anorlu, 2008). However, information
on HPV prevalence globally is not consistent
because there is no uniform scheme of detection.
There are almost no statistics on HPV prevalence
in developing countries due to the lack of data
collection.
There are some studies in the literature looking
at HPV prevalence in general, and it is not
always clear how HPV are tested in their studies.
For instance, it has been estimated that about
6 million new cases of HPV infection are acquired
annually only in the United States, and the
prevalence data implied that around 24 million
American adults; 1 in 5 might be infected with
HPV (Anorlu, 2008). While in South Africa, it
has been estimated that 21 % of women harbour
the HPV, and about 62.8% of invasive cervical
cancer are accredited to HPV 16 and 18 (Summary
report update, 2010). In Nigeria, according
to Nnodu et al, 2010, the prevalence rate of
HPV is 26.3% among the general population, with
cervical cancer prevalence of 24.8%.
While other studies looked at GWs specifically,
and the incidence of GWs in the USA which according
to Hoy et al, 2009, was 1.2/1000 among women,
and 1.1/1000 among men, with the highest incidence
in females aged 20-24 (4.6/1000), and males
aged 25-29 (2.7/1000). According to Brotherton
et al, 2009, in Australia the peak incidence
of GWs was among females aged 20-24 (1.4% reported
GWs in preceding years). According to Moore
et al, 2001, it is estimated that about 111,000
new reported cases of GWs were seen in genitourinary
medicine clinic (GUM) in 1998 in the UK. According
to Edwards, 2008, GWs in UK is rising, and in
2006, it accounted for 22% of all STDs cases
(83,745 of 376,508 cases).
Examine the level of understanding and knowledge
about HPV infection
A comprehensive systemic review of 39 published
studies between 1992 and 2006, carried out by
Klug et al, 2007, covering 19,986 participants,
among the public, students, patients, and health
professionals, in a wide variety of developed
and developing countries (like South Africa,
Mexico, Brazil and some other non specified
South east America), found that about 13-93%
of participants had heard of HPV infection,
and 5-83% knew the association between GWs and
HPV infection, 8-68% of participants knew the
association between HPV and cervical cancer
if the questions were closed, and if the questions
were open only 0.6-11% knew the associations.
Health professionals' knowledge of the association
ranged between 82-100% if closed and 59-87%
if there were open questions. Among the public
some seemed confused between other STDs and
HPV, but generally speaking women and health
professionals demonstrated substantially more
knowledge than men in this review. These broad
ranges demonstrate that knowledge varies in
different site settings.
Attitudes
GWs can considerably influence the psychological
status of the affected individual's self image
and quality of life (QoL). It can lead to stigmatisation,
physical disfigurement and psychological impacts
such as feelings of shame, fear of contagiousness,
depression, isolation, guilt, worry, anger and
sexual impact, with low feeling of self esteem
and dejection in both genders (Hillemanns et
al, 2008, Escalas et al, 2009, Dediol et al,
2009, Mortensen and Larsen, 2010, Daley et al,
2010). However, according to Garland, (2010),
the psychosocial impacts of HPV on men are lacking,
as not much study has been done on men and less
is known about GWs impacts in men according
to Partridge & Koutsky, 2006, while in women
this had been screened and looked at. Thus it
is vital to understand as well as acknowledge
infected men's concerns, and thus more studies
are needed.
Behavioural change, beliefs and practices,
circumcision and HPV
It is well documented in the literature
that HPV is sexually transmitted. The risk of
transmission increases with high risk human
sexual behaviours such as multiple partners
and use of condoms inconsistently. However condoms
do not provide complete protection.
Circumcision has been done for decades as a
religious ritual among Muslim and Jewish people,
and been acknowledged to confer a protection
against many STDs. Male circumcision proved
scientifically to be protective for women against
genital HPV infection (Castellsague et al, 2002).
This finding was supported by Auvert et al,
2009, who reviewed a randomised clinical trial
(RCTs), conducted in South Africa.
This review aimed to look at the
available literature about knowledge,
attitudes and behaviours of women
infected with GWs in different countries,
in order to understand the impact
of the disease. Certainly, healthcare
priorities are different in developing
and developed countries.
From the literature review it has
been found that there is a wide
range of reported levels of knowledge
about HPV internationally. This
project demonstrated significant
gaps in knowledge among many women
worldwide about genital and HPV
infection which varies according
to ethnicity, socio-economic and
other demographic characteristics
(Mays et al, 2000, Cuschieri et
al, 2006).
Australian women in the literature
seemed to be well informed about
genital infection and HPV and this
can possibly be attributed to the
broad educational campaign about
HPV vaccination (Pitts et al, 2010).
Australia was the first country
in April 2007 to introduce the free
quadrivalent Gardasil HPV vaccine
in its campaign which covers the
commonest wart-causing sub-types
(6,11) as well as the commonest
oncogenic subtypes (16,18) for all
women aged 12-26 years and younger
(Donovan et al, 2010). Recently,
Australia reported a rapid decline
in new cases of GWs by 25% among
women and 5% in heterosexual men
in 2008 (Fairley et al, 2009).
The articles that I examined concluded
that HPV diagnosis carried emotional
reactions, and socio-psychological
impacts like fear, worry, detachment
and guilt, because of the cosmetic
and physical disfigurement to the
affected lady's genital area. Thus
it is essential to address psychological
needs (Hillemanns et al, 2008, Escalas
et al, 2009, Dediol et al, 2009,
Mortensen and Larsen, 2010, Daley
et al, 2010).
It is hard to talk about sexuality
openly in any community as its considered
a private thing. This may make it
harder to develop prevention messages
which can be disseminated to the
general public.
Educational intervention which
may be utilised is new technology
like the internet where everyone
can reach out and find the information
they need in private, and people
tend by nature like to read about
sexuality and sexual issues. Also
considering the use of social networks,
mobile texts, and anonymous telephone
hotlines as ways of increased awareness
may be useful. (DeJong et al, 2007).
Implications for policy and
implementations
Adopt the ABC rule, "Abstinence
(from extramarital sex), Being faithful
(to spouses), Condoms (for sexually
active with infected partner)",
as a general rule for cultural norms.
Empower women's confidence about
their rights, with a confidential
approach, for her potential in making
things better for society.
It seems that an almost universal
finding in the literature explored
for this project is the lack of
knowledge about HPV among women
of different ethnic and demographic
backgrounds. This suggests that
there is a strong case for increasing
educational awareness about the
infection and the possible treatment
interventions, including men (GWs
carrier) who seemed to be less aware
compared with women, about genital
and HPV infection.
Health care and service providers
in the community must be educated
and should be sensitive towards
patients' needs and should avoid
adopting a paternalistic and coercive
approach in giving services and
counselling in culturally sensitive
ways, in order to encourage the
patient to seek advice when it is
needed.
Addressing psychological factors
such as embarrassment and stigma,
and the importance of confidentiality
is a vital issue in such patients.
Further communication between HPV
and, or STDs patients, and clinicians
needs to be improved to better understand
and ensure medical care and treatment
at the start.
To date, most studies on attitudes
toward HPV vaccination have been
conducted mostly in the western
countries, thus it is a challenge
to conduct in the developing countries
and compare results with western
cultures about women'a different
ethnicity thoughts. Attitudes will
be influenced by many factors such
as culture, religion and diverse
people'a perceptions, which can
be an obstacle for running vaccination
programs.
The best rule is prevention rather
than cure whereby that would involve
improving public health measures,
such as health promotion and education,
partner identification, condom use,
promotion of safe sex, screening,
and effective public education to
slow down STDs and HPV spread.
Additionally, if only people could
behave, we could say goodbye for
good to every STD.
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