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Chief
Editor -
Abdulrazak
Abyad
MD, MPH, MBA, AGSF, AFCHSE
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Editorial
Office -
Abyad Medical Center & Middle East Longevity
Institute
Azmi Street, Abdo Center,
PO BOX 618
Tripoli, Lebanon
Phone: (961)-3-201901
Email:
Amc_lb@yahoo.com
aabyad@cyberia.net.lb
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Publisher
-
Lesley
Pocock
medi+WORLD International
AUSTRALIA
Email:
lesleypocock@mediworld.com.au
publishermwi@gmail.com
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Editorial
Enquiries -
abyad@cyberia.net.lb
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Advertising
Enquiries -
lesleypocock@mediworld.com.au
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While all
efforts have been made to ensure the accuracy
of the information in this journal, opinions
expressed are those of the authors and do not
necessarily reflect the views of The Publishers,
Editor or the Editorial Board. The publishers,
Editor and Editorial Board cannot be held responsible
for errors or any consequences arising from
the use of information contained in this journal;
or the views and opinions expressed. Publication
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fair dealing for purposes of private study,
research, criticism or review, as permitted
under the Australian Copyright Act, no part
of this program may be reproduced without the
permission of the publisher.
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| WFM
/ MEJFM July-AugustIssue 5, 2025 |
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Alzheimer’s
Disease: Global Insights from Cause
to Care
A Abyad
MD, MPH, MBA, DBA, AGSF , AFCHSE
Consultant, Internal Medicine and
Geriatric, Dar Al Shifa Hospital,
Kuwait Chairman, Middle-East Academy
for Medicine of Aging.
President, Middle East & North
Africa Association on Aging &
Alzheimer’s
Coordinator, Middle-East Primary
Care Research Network
Coordinator, Middle-East Network
on Aging
Correspondence:
Dr Abdulrazak Abyad
Email: aabyad@cyberia.net.lb
Received: June 2025. Accepted:
July 2025; Published:July 20, 2025.Citation:
.Abyad A. Alzheimer’s Disease:
Global Insights from Cause to Care.
World Family Medicine. July-August
2025; 23(5): 69- 76
DOI: 10.5742/MEWFM.2025.805257866
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Abstract
Alzheimer’s
disease (AD) is the most prevalent
cause of dementia worldwide,
accounting for 60-80% of dementia
cases. Characterized by progressive
cognitive decline, functional
impairment, and neuropsychiatric
symptoms, AD places a significant
burden on individuals, caregivers,
and healthcare systems. Advances
in understanding its pathogenesis
have centered on amyloid-beta
(A) plaques, tau pathology,
neuroinflammation, vascular
contributions, and genetic
predispositions. While no
definitive cure exists, emerging
therapies targeting amyloid
and tau pathways offer cautious
optimism. This review integrates
global and regional data,
discusses evolving diagnostic
frameworks, therapeutic progress,
physician-specific challenges,
vascular risk interactions,
and unique considerations
in the Middle East context.
Key words: Alzheimer’s
disease, cause, care,
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